PhD positions (f/m/x) - Edited CAR-T cells

We are looking to support our rapidly growing team as soon as possible: PhD positions (f/m/x) - Edited CAR-T cells

Innere Medizin TV-L: 25 h/week (64,94%) initially limited until March 31, 2027 as part of a third-party funded project
Your salary will be based on TV-L

Your tasks

• Motivated participation in the conceptional and technological development of gene edited CAR-T cells
• Testing in vitro and in vivo in relevant lymphoma models
• Analysis and preparation of data for reports, manuscripts and thesis diissertation for completion of PhD

Your profile

• Completed Bachelor’s and Master‘s Degrees in the field of biomedicine, biology, biochemistry, pharmacy or veterinary medicine
• Strong interest in interdisciplinary work and high motivation for a doctorate (“Dr. rer. nat.” or PhD)
• Very good knowledge and practical experience in the field of molecular biology (CRISPR / Cas, vectors), immunology (cell culture, FACS, ELISA) and mouse handling (FELASA B or equivalent certificate)
• MS Office application programs, FlowJo, GraphPad Prism, very good knowledge of English

Our offer

• A state-of-the-art infrastructure in multidisciplinary, international and new laboratories
• Training in biotechnology and in preclinical research
• Fixed term position from January 1st 2025 until March 31st 2027

The UKK offers a collegial introduction and diverse training and development opportunities as well as an extensive health program for employees. Structured PhD programs are available. There is also a wide range of family support and a day-care center with emergency childcare. In addition, the usual social services of the public service are offered. The UKK is a certified family-friendly university and is committed to promoting women in professional life.
Your future with us
We are one of the leading university hospitals in Germany and network research, teaching and health care at the highest level. That's why many things are a lot bigger for us: the spectrum of exciting development opportunities. The limitless openness with which specialists from all over the world work together here. Or our commitment as an employer to support all employees as best we can in reconciling their job with their goals and life situations.
This is the University Hospital of Cologne: Everything but ordinary.
Your future in detail
The Translational Immuno-Oncology department (chair Prof. Dr. Renata Stripecke) at the Internal Medicine I (Director Prof. Michael Hallek) of the Cologne University Hospital Cologne develops immunotherapies against cancer. We are engineering chimeric antigen receptor T cells (CAR T cells) that kill lymphoma cells and cells infected with Epstein-Barr Virus (EBV). The CRISPR / Cas9 gene editing technique is currently being used to make CAR T cells more effective, safer and more widely available for patients. These gene-edited CAR T cells will be tested pre-clinically in vitro and in vivo. The clinical development of CAR-T cells against lymphomas will follow as a cooperation with several clinicians at the UKK and the University of Dresden.
Further information is available on the internet here.
Applications from female candidates are expressly welcome and will be given priority in the event of equal suitability, competence and professional performance. People with disabilities are welcome to apply and will be treated preferentially in the event of equal suitability and qualification. Contact

Univ.-Prof. Dr. Renata Stripecke
Tel: +49 221 478-15341 Universitätsklinikum Köln AöR
Geschäftsbereich Personal
Kerpener Str. 62
50937 Köln

Uniklinik Köln Karriere Application deadline: 22.12.2024
Job-ID: 1qb4l846
We look forward to receiving your application and getting to know you!